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<C629401> 伯楨生物(bioGenous) Y-27632 dihydrochloride

欄目:生長(zhǎng)因子及小分子(用于類器官培養(yǎng))
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Y-27632 dihydrochloride is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 dihydrochloride attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 dihydrochloride primes human induced pluripotent stem cells (hiPSCs) to selectively differentiate towards mesodermal lineage via epithelial-mesenchymal transition-like modulation.


Y-27632 dihydrochloride

         產(chǎn)品編號(hào)         

產(chǎn)品名稱

     包裝規(guī)格     

      價(jià)格      

C629401   

     Y-27632 dihydrochloride     

100mg

4219.5


產(chǎn)品介紹

Background

Y-27632 dihydrochloride is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 dihydrochloride attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 dihydrochloride primes human induced pluripotent stem cells (hiPSCs) to selectively differentiate towards mesodermal lineage via epithelial-mesenchymal transition-like modulation.

M. W t

320.26

Formula

C??H??Cl?N?O

CAS No

129830-38-2

Storage

- Powder: -20?°C, 3 years
- In solvent: -80?°C, 6 months
- -20?°C, 1 month

Solubility

- DMSO: 33.33 mg/mL (104.07 mM; Need ultrasonic)
- H?O: 100 mg/mL (312.25 mM; Need ultrasonic)