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<C152121> 伯楨生物(bioGenous) SB202190 (FHPI)

欄目：生長因子及小分子（用于類器官培養）
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SB202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits[1][2]. SB202190 induces autophagy[3].


SB202190 (FHPI)

          產品編號       

產品名稱

         包裝規格        

        價格       

C152121   

      SB202190 (FHPI)     

50mg

1440


產品介紹

Background


SB202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits[1][2]. SB202190 induces autophagy[3]. 

M. W t

331.34

Formula

C20H14FN3O

CAS No

152121-30-7

Storage

Powder

- 20°C

3 years

4°C

2 year                                  C20H14FN3O

In solvent

-80°C

6 months                                     


-20°C 

1 month

Solubility

DMSO

100 mg/mL(301.80 mM; Need ultrasonic)


Ethanol

12 mg/mL(36.22 mM)


H2O

< 0.1 mg/mL(insoluble)