產品介紹

bioGenous? 小鼠膽管類器官（分化型）培養試劑盒是一種專為成年干細胞來源的小鼠肝膽管類器官（mLDs）設計的無血清培養基。在小鼠肝膽管類器官擴增培養基中，mLDs 主要由膽管上皮細胞（cholangiocytes）組成，其特征表現為 Sox9 和 Ck19 等標志物的表達。當將擴增培養基替換為分化培養基后，mLDs 可進一步分化為肝細胞，并表達肝細胞特異性標志物，如白蛋白（Albumin）、Cyp3a11 和 Mup20。

Product Description

bioGenous? Mouse Liver Ductal (Differentiation) Organoid Kit is a serum-free culture medium for mouse liver ductal organoids (mLDs) derived from adult stem cells. In mouse liver ductal organoids expansion medium, mLDs predominantly consist of cholangiocytes, characterized by the expression of markers such as Sox9 and Ck19. When the expansion medium is replaced with differentiation medium, mLDs can differentiate into hepatocyte cells, which exhibit hepatocyte-specific markers including Albumin, Cyp3a11, and Mup20. Mouse liver ductal organoids display hallmarks of the ductal epithelium in terms of architecture, cell type composition, and self-renewal dynamics, therefore hold great promise for studies of mouse liver development and disease.